Anti-Allergic & Anti-Inflammatory
Neladex (Eye/Ear Drops)
Each ml contains dexamethasone 1.0 mg, neomycin 3.5 mg, polymyxin В sulphate
- Prophylaxis of postoperative inflammation of anterior eye part.
- Acute and chronic otitis externa and otitis media. Postoperative infectious
complications following ear surgery.
- Keratitis caused by Herpes simplex (dendritic keratitis);
- Viral cornea and conjunctiva (including varicella);
- Micobacterial eye infections;
- Fungal eye diseases;
- Hypersensitivity to any drug ingredients.
The drug is not prescribed in case of not complicated removal of foreign body
The adverse reactions caused by both dexamethasone, and antibacterial components,
as well as their combination can appear at the application of the preparation.
Allergic reactions: itching, eyelid swelling, reddening of conjunctiva (as a
rule it is conditioned by antibacterial component). Adverse reactions due to
- effects on organs of vision: intraocular pressure elevation with possible
subsequent development of glaucoma; formation of back subcapsular cataract;
wound healing slowing-down (perforation of fibrous tunic is possible in topical
glucocorticoids application in diseases causing cornea and sclera thinning).
Therefore administration of Neladex is not recommended in diseases associated
with cornea epithelium defects. Secondary infection (including fungal) may
appear following administration of glucocorticoids in combination with
antibiotics. Secondary bacterial infection may occur as the result of inhibition
of patient's human protective reaction. Glucocorticoids may mask or enhance
underlying infectious process in acute purulent eye diseases. Occurrence of
nonhealing ulcers on cornea following long-term steroid treatment may indicate
on development of fungal invasion.
DOSAGE AND ADMINISTRATION
Eye/ear drops are instilled in 1-2 drops in conjunctival sac 4-6 times per day
at mild forms of infections. At sever forms of infection the drops can be used
every hour; eye drops can be used every hour; as the disease symptoms become
weaken, the quantity of application can be reduced.
At exterior ear canal infections: 4 drops 3-4 times per day.
At infectious complications, connected with surgical operations on ear organs,
and otitis media in 4-10 drops 3-4 times per day.
PREGNANCY AND LACTATION
The drug should be prescribed during pregnancy only if treatment efficacy
justifies potential risk for fetus. It should be determined whether to cease the
breast-feeding during lactation.
5 ml in plastic vial with a dropper and screwing protective cap, equipped with
protective ring. 1 vial with insert in carton box.