Anti-Allergic & Anti-Inflammatory


Neladex (Eye Ointment)
(Dexamethasone/Polymyxin B/Neomycin)

COMPOSITION
Each g contains dexamethasone 1 mg, neomycin 3.5 mg, polymyxin B sulfate 6000 IU.

THERAPEUTIC INDICATIONS
Acute and chronic eye diseases, caused by bacterial infection:
- Blepharitis;
- Conjunctivitis;
- Keratitis;
- Iridocyclitis.
Prophylaxis of postoperative inflammation of anterior eye part.
Acute and chronic otitis externa and otitis media.
Postoperative infectious complications following ear surgery.

CONTRAINDICATIONS
- Keratitis caused by Herpes simplex (dendritic keratitis);
- Viral cornea and conjunctiva (including varicella);
- Micobacterial eye infections;
- Fungal eye diseases;
- Hypersensitivity to any drug ingredients.

ADVERSE EFFECTS
Drug application may be associated with adverse effects, caused by both dexamethazone and antibacterial components and as well as its combination. Allergic reactions: itching, eyelid swelling, reddening of conjunctiva (as a rule it is conditioned by antibacterial component). Adverse reactions due to dexamethazone:
- Effects on organs of vision: intraocular pressure elevation with possible subsequent development of glaucoma; formation of back subcapsular cataract; wound healing slowing-down (perforation of fibrous tunic is possible in topical glucorticosteroids application in diseases causing cornea and sclera thinning). Therefore administration of Neladex is not recommended in diseases associated with cornea epithelium defects. Secondary infection (including fungal) may appear following administration of glucocorticosteroids in combination with antibiotics. Secondary bacterial infection may occur as the result of inhibition of patient's human protective reaction. Glucocorticosteroids may mask or enhance underlying infectious process in acute purulent eye diseases. Occurrence of nonhealing ulcers on cornea following long-term glucocorticosteroid treatment may indicate on development of fungal invasion.

DOSAGE AND ADMINISTRATION
Neladex eye ointment is put into conjunctival sac (cavity between back eyelid surface and front eyebulb surface). Eye ointment is used 4-6 times daily in severe infections; application frequency may be decreased with attenuation of symptoms. The drug is usually prescribed 3-4 times a day in mild infections.

PREGNANCY AND LACTATION
The drug should be prescribed during pregnancy only if treatment efficacy justifies potential risk for fetus.
It should be determined whether to cease the breast-feeding during lactation.

MANUFACTURED FORM
5.0 g of eye ointment is in aluminum tube in a carton box with an annotation-insert.


Anti-Allergic &
Anti-Inflammatory


Clodifen (Eye Drops)

Eyecrol (Eye Drops)

Medexol (Eye/Ear Drops)

Medrolgin (Eye Drops)

Neladex (Eye Ointment)

Neladex (Eye/Ear Drops)

Pallada (Eye Drops)

Tafazol (Eye Drops)




 Events & Exhibitions



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