Treatment of chronic staphylococcal blepharitis with floximed eye drops and ointment

  • On 21 November 2017

Chronic staphylococcal blepharitis is the severe form of eyelid inflammation, characterized by chronicity and frequent exacerbations. Eyesore, itching, warmth, eyelid fatigue and cohesion because of discharge, pyogenic exudate at the corner of eyes, loss of eyelashes (due to inflammation of the hair bulbs), madarosis, trichiasis,  lid lagging and retraction, meibomitis and development of hordeolum, corneal lesions: this is the long list of complaints that characterizes the disease. Pathogenic flora is crucial in the disease etiology, therefore rational antimicrobial treatment is warrant of full patient recovery.

For treatment of chronic staphylococcal blepharitis we used Floximed 0.3% eye drops for instillation and ointment for topical application.

We had 14 patients with chronic staphylococcal blepharitis under our observation. In the patient history each individual had complaints about chronic course of the disease, frequent exacerbations and inefficiency of the prior treatments.

Examination methods:

For every patient standard examination methods were undertaken: visometry, ophthalmoscopy, lid and eyeball biomicroscopy, bacteriology study of the discharge, Schirmer`s test, microscopy study of eyelashes.

Objective results of the patients examination. Number of the patients
Hyperemia and thickening of eyelid corners 14
Superficial pyogenic exudate on the eyelash borders 14
Bleeding ulcers covered with pyogenic exudate 6
Meibomitis 4
Hordeolum 5
Trichiasis 11
Madarosis 3
Ectropion 4
Pyogenic eye discharge 14
Conjunctival hyperemia 14
Corneal infiltration of staphylococci near the limbus 5
Positive Schirmer`s test 14

According to bacteriology studies, Staphylococcus aureus was revealed in every patient.

From the table above it is obvious that disease was expressed by various symptoms . It is important to mention that each patient had “dry eyes syndrome” xerophthalmia, in our opinion caused by absolute dysfunction of the Meibomian glands, but at the initial period because of profuse eye discharge we were avoiding use of lubricating agents.

Treatment Regimen:

Every patient was prescribed Floximed eye drops for local instillation 6 times/day for one week, 4 times /day for one week, 3 times/day for one week.

Floximed ointment for topical application in lower fornix region and at the lid corners 2 times/day for 2 weeks and once daily for one week. After this 10 procedures of phonophoresis with Floximed ointment was conducted with day after day regimen.

In our treatment plan we also included warm compresses of eyelid lotion and eyelid massage. No allergic reactions were detected in each patient toward Floximed.

After cessation of eye discharge, lubricating medications were added to the treatment regimen.

Conclusions:

  1. 3% eye drops and ointment of Floximed is effective for treatment of chronic Staphylococcal blepharitis.
  2. For treatment of chronic Staphylococcal blepharitis phonophoresis is highly recommended with use of Floximed ointment
  3. Floximed ointment and eye drops faster resolution of Staphylococcal infiltrations on the cornea, caused by chronic Staphylococcal

References:

  1. Майчук ю.ф. Глазные инфекции //РМЖ. – 1999 Т.7. #1 (85) – С 16-20
  2. майчук ю.ф. юхаков А.М. юхаков А.М. Оптимизация антибактериалъной терапии при гпазных инфекциях // Рефракционная хирургия и офталъмология М.2002 – Г(2) – C44-52

NINO KARANADZE, MD, PhD, Assistant Professor

Tbilisi State Medical University

Department of Eye Diseases

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